Planaria are ideal model organisms for studying regeneration and aging because they both have the remarkable ability to completely regenerate from a small fragment of tissue and because they are essentially immortal. Neoblasts, totipotent adult stem cells, are entirely responsible for the planaria's regenerative capabilities and immortality and possess a superset of the capability of human embryonic stem (ES) cells. We seek to learn the neoblasts' secrets and eventually apply them to human cells. Selected candidates will apply RNA interference (RNAi) to elucidate fundamental mechanisms of aging and regeneration.
The ideal undergraduate candidate would have at least a sophomore standing (although everyone will be considered), a good understanding of basic biology and some knowledge of molecular biology. Prior lab experience is not necessary but would be advantageous. Selected applicants will receive training in basic molecular biology and how to design experiments. Because of the time investment needed to train any volunteer to be self-sufficient in basic lab techniques and thinking, we require at minimum a 6 month commitment to the lab.
If you would like to apply please write a brief description about yourself, why you would be a good candidate for this position, and a resume to jlei@regensci.org. There may be opportunities for independent study credit in conjunction with a faculty sponsor at Stanford or Berkeley, depending upon the particular project and faculty member. Graduate students are also welcome to apply if arrangements can be made with your faculty advisor. Regenerative Sciences Institute is a small 501(C)(3) non-profit located in Sunnyvale, CA about 10 miles from Stanford University.