BTE-SV 2011-12

BTE-SV_Logo

 DNA Nanomesh For Cancer Therapy

NETosis is a recently discovered form of pathogen induced cell death and one of the first lines of defense as part of the innate immunity. Neutrophils release nuclear or mitochondrial chromatin to create neutrophil extracelluar traps (NETs). Attached to the NETs is an array of granular antimicrobial molecules that trap and kill bacteria, fungus, or protozoan invaders. The NETs are assembled around foreign invaders, creating a cage-like DNA structure. For the 2011-12 BTE-SV project, we propose the creation of a synthetic biological adaptation of NETs specifically targeted to capture and destroy cancer cells.

netosis2

nets 2

 

 

Cancer cells are nor recognized by a patient’s immune system because they are not foreign entities.They have simply gained the abilities to overcome normal cell regulation. Hence, under normal physiological conditions, neutrophils do not target cancer cells.

 

 

Many geometrical shapes and DNA lactices can be created beginning with a simple DNA subunit. The inherent nucleotide base pairing, and the design of the subunit, allows arrays to spontaneously form in an aqueous environment.

 

DNA cubeDNA cross

 

For specific targeting of synthetic NET formation, we will utilize an anti-HER2 scfv antibody against breast cancer cells.  The scfv is fused to a DNA binding domain, lexA, which will allow the antibody to bring along a cargo of DNA subunits and apoptotic agents.

anti-her2 scfv-lexa-cytotox

Interns

2011
Harsimran Sidhu, Mission San Jose High School 2012
Ayako Ohoka, Lynbrook High School 2012

2012
Rebecca Sze, Leland High School 2013
Evan Xue, Lynbrook High School 2013

24,213 Comments:

  1. XEvil – the best captcha solver tool with unlimited number of solutions, without thread number limits and highest precision!
    XEvil 5.0 support more than 12.000 types of image-captcha, included ReCaptcha, Google captcha, Yandex captcha, Microsoft captcha, Steam captcha, SolveMedia, ReCaptcha-2 and (YES!!!) ReCaptcha-3 too.

    1.) Flexibly: you can adjust logic for unstandard captchas
    2.) Easy: just start XEvil, press 1 button – and it’s will automatically accept captchas from your application or script
    3.) Fast: 0,01 seconds for simple captchas, about 20..40 seconds for ReCaptcha-2, and about 5…8 seconds for ReCaptcha-3

    You can use XEvil with any SEO/SMM software, any parser of password-checker, any analytics application, or any custom script:
    XEvil support most of well-known anti-captcha services API: 2Captcha, RuCaptcha, AntiGate.com (Anti-Captcha.com), DeathByCaptcha, etc.

    Interested? Just search in Google “XEvil” for more info
    You read this – then it works! ;)))

    http://xrumersale.site/

    Regards, Lolitaboymn6769

  2. XEvil – the best captcha solver tool with unlimited number of solutions, without thread number limits and highest precision!
    XEvil 5.0 support more than 12.000 types of image-captcha, included ReCaptcha, Google captcha, Yandex captcha, Microsoft captcha, Steam captcha, SolveMedia, ReCaptcha-2 and (YES!!!) ReCaptcha-3 too.

    1.) Flexibly: you can adjust logic for unstandard captchas
    2.) Easy: just start XEvil, press 1 button – and it’s will automatically accept captchas from your application or script
    3.) Fast: 0,01 seconds for simple captchas, about 20..40 seconds for ReCaptcha-2, and about 5…8 seconds for ReCaptcha-3

    You can use XEvil with any SEO/SMM software, any parser of password-checker, any analytics application, or any custom script:
    XEvil support most of well-known anti-captcha services API: 2Captcha.com, RuCaptcha.Com, AntiGate (Anti-Captcha), DeathByCaptcha, etc.

    Interested? Just search in YouTube “XEvil” for more info
    You read this – then it works! ;))

    Regards, Lolityboymn5030

    XEvil.Net

  3. XEvil – the best captcha solver tool with unlimited number of solutions, without thread number limits and highest precision!
    XEvil 5.0 support more than 12.000 types of image-captcha, included ReCaptcha, Google captcha, Yandex captcha, Microsoft captcha, Steam captcha, SolveMedia, ReCaptcha-2 and (YES!!!) ReCaptcha-3 too.

    1.) Flexibly: you can adjust logic for unstandard captchas
    2.) Easy: just start XEvil, press 1 button – and it’s will automatically accept captchas from your application or script
    3.) Fast: 0,01 seconds for simple captchas, about 20..40 seconds for ReCaptcha-2, and about 5…8 seconds for ReCaptcha-3

    You can use XEvil with any SEO/SMM software, any parser of password-checker, any analytics application, or any custom script:
    XEvil support most of well-known anti-captcha services API: 2Captcha.com, RuCaptcha, AntiGate (Anti-Captcha), DeathByCaptcha, etc.

    Interested? Just search in YouTube “XEvil” for more info
    You read this – then it works! 🙂

    Regards, Loliteboymn1314

    XEvil.Net

  4. XEvil – the best captcha solver tool with unlimited number of solutions, without thread number limits and highest precision!
    XEvil 5.0 support more than 12.000 types of image-captcha, included ReCaptcha, Google captcha, Yandex captcha, Microsoft captcha, Steam captcha, SolveMedia, ReCaptcha-2 and (YES!!!) ReCaptcha-3 too.

    1.) Flexibly: you can adjust logic for unstandard captchas
    2.) Easy: just start XEvil, press 1 button – and it’s will automatically accept captchas from your application or script
    3.) Fast: 0,01 seconds for simple captchas, about 20..40 seconds for ReCaptcha-2, and about 5…8 seconds for ReCaptcha-3

    You can use XEvil with any SEO/SMM software, any parser of password-checker, any analytics application, or any custom script:
    XEvil support most of well-known anti-captcha services API: 2Captcha, RuCaptcha.Com, AntiGate.com (Anti-Captcha.com), DeathByCaptcha, etc.

    Interested? Just search in Google “XEvil” for more info
    You read this – then it works! 🙂

    Regards, Lolityboymn9908

    XEvil.Net

  5. MEET HOT LOCAL GIRLS TONIGHT WE GUARANTEE FREE SEX DATING IN YOUR CITY CLICK THE LINK:
    FREE SEX

  6. http://buystromectolon.com/ – ivermectin for rosacea

  7. https://buytadalafshop.com/ – generic 5mg cialis best price

  8. I have read so many articles or reviews concerning the blogger
    lovers except this article is really a fastidious article, keep
    it up.

    Feel free to visit my site :: verizon promo

  9. I like the helpful information you supply on your articles.
    I’ll bookmark your blog and test again here frequently.
    I’m somewhat sure I will learn lots of new stuff right here!
    Good luck for the next!

    Also visit my web blog: black friday shopping (Norma)

  10. Hello there, just became alert to your blog
    through Google, and found that it is truly informative. I?m gonna watch out for brussels.
    I?ll appreciate if you continue this in future. Numerous people
    will be benefited from your writing. Cheers!

    Here is my page :: pmp exam stress (Paige)

  11. I really like your blog.. very nice colors & theme. Did you make
    this website yourself or did you hire someone to do it for you?
    Plz answer back as I’m looking to construct my own blog and would like to know where u got this from.
    thank you

    My website time management

  12. I go to see everyday some web pages and sites to read content, except this website offers feature based writing.

    my site – create a multiple choice exam

  13. Fantastic tips. Appreciate it! the college essay undergraduate coursework dissertation research grants

  14. Cheers, I like this!
    good essay writing website
    writing paper

  15. Appreciation to my father who informed me concerning this webpage, this weblog is genuinely amazing.

    my web blog :: bar exam prep; Derek,

  16. You have brought up a very good details, thanks for the post.

    Take a look at my web-site printable coupons

  17. I really treasure your piece of work, Great post.

    My web page :: bread coupons (Leslie)

  18. Position certainly applied.! writing a synthesis essay write my papers academic research paper

  19. Oh my goodness! Incredible article dude! Many thanks, However I am experiencing
    troubles with your RSS. I don’t know the reason why I
    can’t subscribe to it. Is there anybody getting the same RSS issues?
    Anybody who knows the solution will you kindly respond?

    Thanks!!

    my website telecom certifications (Sabine)

  20. I go to see day-to-day some blogs and information sites to read posts, however this weblog
    offers feature based writing.

    Feel free to surf to my web blog; exam tips; Geneva,

  21. Bladder Infection Zithromax

  22. Thankfulness to my father who shared with me on the topic of this weblog,
    this webpage is actually remarkable.

    My web page :: pmp certificate

  23. Usually I don’t read post on blogs, but I would like to say that this write-up very pressured me to take a
    look at and do so! Your writing style has been surprised me.
    Thank you, quite nice article.

    Also visit my webpage pharmacy technician certification exam

  24. Many thanks, Very good information!
    custom written essay https://agbsl.pro/en/page-v523lrma392fn.html how to write a winning scholarship essay
    [url=http://danandmisono.com/2009/12/28/new-york/comment-page-5/#comment-61140]how to write a contrast essay n33rnf[/url] 4571d74

  25. [url=https://viagralf.com/]safe buy viagra online[/url]

  26. I love your blog.. very nice colors & theme. Did you make this website yourself or did you hire someone to do it for you?
    Plz answer back as I’m looking to design my own blog and
    would like to find out where u got this from.
    appreciate it

    Feel free to visit my blog post cpc exam questions

  27. Amazing content. Thanks.
    how to write a research argument paper https://cbd-oil-trust.com/en/topic-b54eas0n60gxg.html issues to write a research paper on
    [url=http://zmrzlina.kunetice.cz/fotogalerie.php?mn_post=40#c-180879&mn_msg=c_added#c-180989]why go to college essay m912np[/url] 8180b1d

  28. I precisely wanted to thank you so much once again. I am not sure the things I would’ve tried
    without those ways discussed by you over my situation. It
    absolutely was an absolute alarming setting for me, however ,
    seeing a expert manner you handled it took me how to cram for an exam – Katherine – weep with happiness.
    Now i’m grateful for the help and wish you know what an amazing
    job you’re carrying out teaching others by way of
    your web blog. I’m certain you have never come across all of us.

  29. Helpful data. Appreciate it!
    buy essay paper https://paydayloansbbvtop.com/en/page-o27dzadn16fth.html phd research proposal
    [url=http://audreycleo.com/?p=4613&cpage=1192#comment-11117753]writing essay service q18cvn[/url] 571d746

  30. Normally I do not learn article on blogs, but I
    wish to say that this write-up very pressured me to take a look at and do it!

    Your writing style has been surprised me. Thanks, very nice post.

    Also visit my site; mblex practice exams (Omar)

  31. Thanks to my father who stated to me regarding this web site, this website is
    actually amazing.

    Here is my web-site – final exam [Shayne]

  32. Oh my goodness! Awesome article dude! Many thanks, However I am experiencing problems with your RSS.
    I don’t know the reason why I can’t subscribe to
    it. Is there anybody else having similar RSS issues?
    Anyone who knows the solution will you kindly respond?
    Thanks!!

    Here is my website: study right (Ardis)

  33. Paragraph writing is also a fun, if you be familiar with then you can write if not it is complex
    to write.

    Take a look at my web site: microsoft certification training (Jeffery)

  34. hey there and thank you for your info ? I’ve certainly picked
    up anything new from right here. I did however
    expertise several technical points using this website, as I experienced to reload the website a lot of times previous to I could get
    it to load correctly. I had been wondering if your web host is
    OK? Not that I’m complaining, but slow loading instances times will very frequently
    affect your placement in google and could damage your quality score if ads and marketing with
    Adwords. Well I am adding this RSS to my e-mail and can look out for a lot more of your respective intriguing content.
    Ensure that you update this again soon.

    Also visit my blog post microsoft certification tests (Foster)

  35. hello there and thank you for your information ?
    I’ve definitely picked up something new from right here.
    I did however expertise some technical points using
    this site, as I experienced to reload the site lots
    of times previous to I could get it to load properly.
    I had been wondering if your web hosting is OK? Not that
    I’m complaining, but slow loading instances times will very frequently affect your placement in google
    and could damage your high quality score if ads and marketing with Adwords.
    Anyway I am adding this RSS to my email and could
    look out for much more of your respective interesting content.
    Make sure you update this again very soon.

    my webpage … vcp510 exams, Ulysses,

  36. can i buy ivermectin over the counter ivermectin lotion

  37. I pay a visit each day a few web pages and blogs to read articles, however this weblog offers quality based
    articles.

    Here is my web-site … phlebotomy training, Katherina,

  38. hey there and thank you for your information ? I have definitely picked up something new from right here.
    I did however expertise several technical issues using this web site, since I
    experienced to reload the website a lot of times previous to I could get it to load correctly.
    I had been wondering if your hosting is OK? Not that I’m complaining, but sluggish loading instances times will very frequently affect your placement
    in google and could damage your high-quality
    score if advertising and marketing with Adwords. Anyway I am adding this RSS to my e-mail and can look out
    for much more of your respective intriguing content.
    Ensure that you update this again very soon.

    Stop by my website – ccna certification (Scarlett)

  39. I love your blog.. very nice colors & theme. Did you design this website yourself or did you hire someone to
    do it for you? Plz answer back as I’m looking to design my own blog and would like to
    find out where u got this from. kudos

    Here is my web-site: Certification Test

  40. Way cool! Some very valid points! I appreciate you writing
    this post and the rest of the website is really
    good.

    Here is my web site … exam stress – Samara

  41. Greetings! I’ve been following your blog for some time
    now and finally got the courage to go ahead and give you a shout out from Dallas Texas!
    Just wanted to say keep up the good work!

    Here is my homepage – networking exams centred; Tabitha,

  42. You are so cool! I don’t think I’ve read a single
    thing like this before. So nice to find another person with a
    few genuine thoughts on this topic. Seriously.. many thanks for
    starting this up. This site is something that’s needed on the web, someone with a bit of originality!

    my site: Mcse Jobs

  43. I love your blog.. very nice colors & theme. Did you design this website yourself or did
    you hire someone to do it for you? Plz answer back as
    I’m looking to create my own blog and would like to know where u
    got this from. cheers

    Also visit my blog: test anxiety hypnosis (Jed)

  44. I pay a visit each day a few blogs and sites to read articles, except this
    webpage offers feature based posts.

    Here is my page; answering questions (Tom)

  45. Hello there, just became aware of your blog through Google, and found that it’s truly informative.

    I am gonna watch out for brussels. I?ll be grateful if you
    continue this in future. Many people will be benefited from your
    writing. Cheers!

    Also visit my webpage … nclex rn test (Quinn)

  46. First off I want to say superb blog! I had a quick question that I’d like to ask if you don’t mind.
    I was interested to find out how you center yourself and clear your mind before writing.
    I have had a hard time clearing my thoughts in getting my ideas out there.
    I truly do enjoy writing but it just seems like the first 10 to 15 minutes are wasted simply just trying to figure out
    how to begin. Any ideas or tips? Thank you!

    Here is my web site help pass driving exam, Ila,

  47. https://prednisonebuyon.com/ – prednisolone pricing

  48. provigil cost how long does modafinil last [url=https://modafinilprovigiliq.com/ ]provigil prescription [/url]

  49. ivermectin where to buy where can i buy [url=https://ivermectindelta.com/# ]ivermectin dosage chart for humans [/url]

  50. Oh my goodness! Amazing article dude! Thanks, However I am having difficulties
    with your RSS. I don’t understand why I can’t subscribe to it.
    Is there anybody having identical RSS issues?

    Anyone that knows the answer can you kindly respond?
    Thanks!!

    Also visit my web blog: 312-50 exam (Ben)

  51. Usually I don’t learn post on blogs, but I wish to say that this write-up very forced me
    to take a look at and do so! Your writing style has been surprised me.
    Thanks, very great post.

    my web blog :: exam material, Leonida,

  52. Way cool! Some very valid points! I appreciate you penning this post and the
    rest of the site is really good.

    my web-site: nortel certifications learning

  53. Hello, i believe that i noticed you visited my website so i came
    to ?go back the desire?.I’m trying to find things to improve my website!I guess its good enough to use a few
    of your concepts!!

    Also visit my homepage: cna certification (Elwood)

  54. nuvigil vs provigil modafinil otc [url=https://modafinilprovigilis.com/ ]modafinil schedule [/url]

  55. I love your blog.. very nice colors & theme.
    Did you create this website yourself or did you hire someone tips To answer the gamsat questions do it for you?
    Plz answer back as I’m looking to create my own blog and would like
    to know where u got this from. thank you

  56. I couldn’t resist commenting. Very well written!

  57. Greetings! Very helpful advice within this post!
    It’s the little changes that will make the greatest changes.
    Thanks a lot for sharing!

  58. Heya i am for the first time here. I found this board and I in finding It really useful
    & it helped me out a lot. I am hoping to provide something
    back and help others such as you aided me.

  59. I really like your blog.. very nice colors & theme.

    Did you create this website yourself or did you hire someone to do it for you?

    Plz respond as I’m looking to design my own blog and would like to know where u got this
    from. cheers

    Review my webpage project management professional; Cora,

  60. I don’t even know the way I ended up right here, but I assumed this
    put up was great. I do not recognise who you might be however certainly you are going to a famous blogger in case you aren’t already.
    Cheers!

    Here is my web-site: preparation tips

  61. I visit daily some web sites and websites to read articles
    or reviews, except this website provides quality based content.

    Also visit my page – study guide; stackoverflow.com,

  62. Oh my goodness! Impressive article dude! Many thanks, However I am experiencing problems with your
    RSS. I don’t know the reason why I am unable to subscribe to
    it. Is there anybody getting the same RSS issues? Anyone
    who knows the solution will you kindly respond? Thanks!!

    Take a look at my site :: hp0-j23 exam (Amie)

  63. Paragraph writing is also a fun, if you know then you can write or else
    it is complicated to write.

    Also visit my web site nortel study guide (Maritza)

  64. Heya i am for the first time here. I came across this board and I in finding It
    truly useful & it helped me out a lot. I’m hoping to give something back and help others like you aided me.

  65. News about Iran from an unbiased and accurate source.
    Updated daily with the latest from Iran’s economy, politics
    and business

  66. I always used to study article in news papers but now
    as I am a user of internet thus from now I am using
    net for articles, thanks to web.

  67. I’m just writing to let you understand of the excellent experience my friend’s princess undergone studying the
    blog. She came to understand a good number of details, with the inclusion of what
    it is like to have a marvelous giving spirit to make other folks
    with ease pmp exam comprehend
    selected grueling things. You really surpassed
    visitors’ expected results. Many thanks for providing such practical, trusted, edifying and unique tips about the topic to Gloria.

  68. I read this paragraph fully on the topic of the comparison of latest
    and earlier technologies, it’s amazing article.

  69. I pay a visit every day some websites and information sites to read content, however this blog offers feature
    based content.

    My web site … pmp sample questions

  70. Excellent web site you’ve got here.. It’s difficult to
    find high quality writing like yours nowadays.
    I honestly appreciate people like you! Take care!!

  71. Hello my friend! I wish to say that this post is awesome, great written and come with approximately all important infos.
    I would like to see extra posts like this.

    My webpage itil certification – Elyse

  72. I do not even understand how I finished up right here, but I
    believed this publish used to be good. I don’t recognize who you might be but
    definitely you are going to a well-known blogger if you happen to are not
    already. Cheers!

    Feel free to surf to my web blog … pmp certification (Melvin)

  73. hydroxychloroquine coronavirus trump hydroxychloroquine [url=https://plaquenilotc.com/# ]hydroxychloroquine malaria [/url]

  74. Its such as you learn my mind! You appear to know so much about this,
    such as you wrote the e book in it or something. I believe that you
    simply could do with some % to power the message house a bit, but
    other than that, this is excellent blog. An excellent read.
    I will definitely be back.

  75. ???? ??????? ??? ??? . ?????? ???? ?? ?????? ???? ????? ?? ?? ????? my web blog: ravanbazar

  76. modafinil dosage modafinil warnings [url=https://provigilpillsonline.com/ ]buy provigil [/url]

  77. ???? ??????? ??? ??? . ?????? ???? ?? ?????? hirbodclinic.com ?? ?? ????? my web blog: ????????

  78. Excellent post. I used to be checking continuously this blog and I am inspired!
    Extremely useful information specifically the last phase :
    ) I handle such info much. I used to be seeking this certain info for a very lengthy time.
    Thank you and good luck.

  79. ???? ??????? ??? ??? . ?????? ???? ?? ?????? hirbodclinic.com ?? ?? ????? my web blog: ??????????????

  80. Cialis Frei Erhaltlich Lander

  81. Howdy! I just wish to offer you a big thumbs up for the great info you have got
    right here on this post. I am returning to your website
    for more soon.